Difference between `python setup.py test` and `python -munittest discover -v` in search for binary modules

M2Crypto uses still python setup.py test for calling its test suite. When I tried to switch to python -munittest discover -v I get this error:

[   25s] + PYTHONPATH=/home/abuild/rpmbuild/BUILDROOT/python-M2Crypto-0.36.0-0.x86_64/usr/lib64/python3.8/site-packages
[   25s] + PYTHONDONTWRITEBYTECODE=1
[   25s] + python3 -m unittest discover -s tests -v
...
[   25s] ======================================================================
[   25s] ERROR: test_aes (unittest.loader._FailedTest)
[   25s] ----------------------------------------------------------------------
[   25s] ImportError: Failed to import test module: test_aes
[   25s] Traceback (most recent call last):
[   25s]   File "/usr/lib64/python3.8/unittest/loader.py", line 436, in _find_test_path
[   25s]     module = self._get_module_from_name(name)
[   25s]   File "/usr/lib64/python3.8/unittest/loader.py", line 377, in _get_module_from_name
[   25s]     __import__(name)
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/tests/test_aes.py", line 9, in <module>
[   25s]     from M2Crypto import m2
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/M2Crypto/__init__.py", line 30, in <module>
[   25s]     from M2Crypto import (ASN1, AuthCookie, BIO, BN, DH, DSA, EVP, Engine, Err,
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/M2Crypto/ASN1.py", line 15, in <module>
[   25s]     from M2Crypto import BIO, m2, py27plus, six
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/M2Crypto/BIO.py", line 9, in <module>
[   25s]     from M2Crypto import m2, py27plus, six
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/M2Crypto/m2.py", line 30, in <module>
[   25s]     from M2Crypto.m2crypto import *
[   25s]   File "/home/abuild/rpmbuild/BUILD/M2Crypto-0.36.0/M2Crypto/m2crypto.py", line 13, in <module>
[   25s]     from ._m2crypto import *
[   25s] ModuleNotFoundError: No module named 'M2Crypto._m2crypto'
...

abuild@stitny:~> ls /home/abuild/rpmbuild/BUILDROOT/python-M2Crypto-0.36.0-0.x86_64/usr/lib64/python3.8/site-packages/M2Crypto
ASN1.py        BN.py   EC.py      Err.py  Rand.py   X509.py      _m2crypto.cpython-38-x86_64-linux-gnu.so  httpslib.py  m2urllib.py     six.py
AuthCookie.py  DH.py   EVP.py     RC4.py  SMIME.py  __init__.py  callback.py                               m2.py        m2urllib2.py    threading.py
BIO.py         DSA.py  Engine.py  RSA.py  SSL       __pycache__  ftpslib.py                                m2crypto.py  m2xmlrpclib.py  util.py
abuild@stitny:~>

The binary module is certainly in the directory included in sys.path, but that is apparently not enough. Is there some other variable I need to set ($PYTHONCPATH or something)? How are binary modules located?