Just a quick heads-up: Our local mirror was also affected by this change, as I reported here: [solved] PIP fetches from files.pythonhosted.org despite local mirror was specified This was difficult to debug, as accessing the mirror via curl worked as expected, but downloads via pip were still redirected to files.pythonhosted.org although the index was correctly fetched. I didn’t find this thread by my search keywords, so I thought, reporting back here might help users find this in the future 