I think one thing most of us can agree on is that a unification will require a significant amount of effort (whether we’re talking about a new rustup/Cargo-like experience, unifying on a tool such as Poetry/hatch/PDM and adding native build extension support, etc.).
Would a good outcome of this discussion be a proposal to the PSF to fund this? Clearly many users care about this and many of them work at companies, so perhaps we should give commercial companies to opportunity to fund this effort to help make tangible progress.