It would be useful to add a WASM runtime to the standard library. Some useful code is written in C, Ruts, or other languages that are usually compiled to native code. That code could be compiled to WASM and executed at a moderate speed on all platforms instead of having to compile separate C extensions for all platforms your Python code might need to run on.
These runtime’s APIs are simple enough that it might be possible to have different WASM interpreters (depending on which Python implementation you are using) while keeping the same Python interface.
https://github.com/bytecodealliance/wasm-micro-runtime is one runtime. If it was incorporated into a Python extension module I think you’d want to poke around here: https://github.com/bytecodealliance/wasm-micro-runtime/tree/master/core/iwasm/common/arch to be able to expose Python functions to the runtime, without having to fake it with cffi or ctypes style techniques.